Exactly.Exactly.Exactly.There is not enough frontal area on the e60 for a properly sized intercooler to reduce the charged air temp, so that will lead to pre-ignition especially with 12:1 CR. The PCM/DME will command max spark retard, so I can see situations where there is less power with a twin turbo setup than stock. I'm really interested in the build.I don't get this - why not just get an F10? Slapping some turbos on a very high compression engine that already has issues with heat management seems like 2000s honda civic thing to do. You'll melt something down sooner or later, not unlike the e85 conversion guys.
Why would you need a new manifold? There's not enough space for twin intercoolers anyway.