If there is a good "thunk", then check the rear axle beam bushes.
If you mean the engine itself, then this I think is fairly normal. For instance, a little game; Try sitting parked somewhere, in neutral, then press the accelarator to go from idle (850ish rpm) to exactly 1000rpm, the first white line.....
Can`t be done. You add more and more pressure to the mechanical cable, but there are six throttle bodies, one per cylinder, which is normal only on bikes and M-Cars, so the cable doesn`t move. Suddenly you have enough pressure to open all six, and the revs jump to 1100+.
Try it the other way is easier, drop the revs slowly to 1000rpm, this is sometimes do-able.
That is why driving the M5 smoothly at low speed around town or in a traffic jam is a talent. The mechanical nature of the throttle system does cause those clunks and jerks when coming off and on the throttle lightly at low speed.
Sometimes I get a "harmonic", especially at very low speed in first, for example in a traffic jam at walking pace, where the car "bounces" forward and back as the play in the gearbox and transmission argues with the car trying to be on and off the idle at 900-1000rpm.
Then again, my car just might be knackered!!! LOL
Ivan.