Loads.
Why? The resale value of the 3.8 M5 will be devastated.
You`ll get more torque, but the BHP is similar, so the overall speed increase will not be worth the aggravation.
This has been done a few times in 535i cars, but to do so on an M5 would be considered sacrilage.
Still, if you want to do it, you should buy the entire 750s wiring loom and computer components.
Remember that the M5 gearbox is unique to the M5, so any modifications or adapters that need to be obtained to mate it to the V12 are going to be custom made.
To my knowledge, no-one has ever wrecked an M5 by using it as a donor car for the V12, so you are probably the first to do so. The problem is because as you are the first, no-one has
ever made the parts to link the box to the engine!!
I`m not even going to continue.
To take a M5 3.8, pay for a V12, add months of aggro making it go in, only to be left with a car of approximately the same performance but worth a whole lot less, and living ***** to insure, is a bad move.
What you need to do is sell the car, add the money you have for the 750s engine and ancillaries, then think long and hard about an Alpina B10 BiTurbo if you want the E34 shape, or have a looksee for how much the first of the E39 cars are selling for now.
Welcome to bmwm5.com. This is not an attack on you, maybe I am too strong with my words above, but I stress to you that for more power, choose another car instead of what you are proposing for the 5.
Ivan.